BAIT
NXF1
MEX67, TAP
nuclear RNA export factor 1
GO Process (2)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
IMPA1
IMP, IMPA
inositol(myo)-1(or 4)-monophosphatase 1
GO Process (6)
GO Function (7)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Evolutionary development of redundant nuclear localization signals in the mRNA export factor NXF1.
In human cells, the mRNA export factor NXF1 resides in the nucleoplasm and at nuclear pore complexes. Karyopherin β2 or transportin recognizes a proline-tyrosine nuclear localization signal (PY-NLS) in the N-terminal tail of NXF1 and imports it into the nucleus. Here biochemical and cellular studies to understand the energetic organization of the NXF1 PY-NLS reveal unexpected redundancy in the nuclear ... [more]
Mol. Biol. Cell Dec. 01, 2011; 22(23);4657-68 [Pubmed: 21965294]
Throughput
- Low Throughput
Additional Notes
- figure 1.
- table 2.
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| IMPA1 NXF1 | Reconstituted Complex Reconstituted Complex An interaction is detected between purified proteins in vitro. | Low | - | BioGRID | 697175 |
Curated By
- BioGRID