BAIT

GFER

ALR, ERV1, HERV1, HPO, HPO1, HPO2, HSS
growth factor, augmenter of liver regeneration
GO Process (2)
GO Function (3)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

COPS2

ALIEN, CSN2, SGN2, TRIP15
COP9 signalosome subunit 2
UPS Project
GO Process (3)
GO Function (2)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-Western

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.

Publication

Hepatopoietin interacts directly with COP9 signalosome and regulates AP-1 activity.

Wang Y, Lu C, Wei H, Wang N, Chen X, Zhang L, Zhai Y, Zhu Y, Lu Y, He F

Hepatopoietin (HPO)/augmenter of liver regeneration (ALR) is a specific hepatotrophic growth factor, which plays a key role in liver regeneration. Our previous study indicated that HPO executes its function by an inter-reactive network of the autocrine, paracrine and endocrine pathways. Recently, we have demonstrated that intracellular HPO interacts with Jun activation domain-binding protein 1 (JAB1) and leads to potentiation of ... [more]

FEBS Lett. Aug. 13, 2004; 572(1);85-91 [Pubmed: 15304329]

Throughput

  • Low Throughput

Curated By

  • BioGRID