BAIT

COPS2

AI315723, C85265, Csn2, Sgn2, TRIP-15, Trip15, RP23-368I1.3
COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana)
Mus musculus
PREY

NAP1L1

AA407126, AI256722, D10Ertd68e, NAP-1
nucleosome assembly protein 1-like 1
GO Process (0)
GO Function (3)
GO Component (3)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Mus musculus

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

The nucleosome assembly activity of NAP1 is enhanced by Alien.

Eckey M, Hong W, Papaioannou M, Baniahmad A

The assembly of nucleosomes into chromatin is essential for the compaction of DNA and inactivation of the DNA template to modulate and repress gene expression. The nucleosome assembly protein 1, NAP1, assembles nucleosomes independent of DNA synthesis and was shown to enhance coactivator-mediated gene expression, suggesting a role for NAP1 in transcriptional regulation. Here, we show that Alien, known to ... [more]

Mol. Cell. Biol. May. 01, 2007; 27(10);3557-68 [Pubmed: 17339334]

Throughput

  • Low Throughput

Curated By

  • BioGRID