BAIT
KCNA2
HBK5, HK4, HUKIV, KV1.2, MK2, NGK1, RBK2, RP11-284N8.1
potassium voltage-gated channel, shaker-related subfamily, member 2
GO Process (6)
GO Function (3)
GO Component (10)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
KCNA2
HBK5, HK4, HUKIV, KV1.2, MK2, NGK1, RBK2, RP11-284N8.1
potassium voltage-gated channel, shaker-related subfamily, member 2
GO Process (6)
GO Function (3)
GO Component (10)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Kv2.1 and electrically silent Kv6.1 potassium channel subunits combine and express a novel current.
Heteromultimer formation between Kv potassium channel subfamilies with the production of a novel current is reported for the first time. Protein-protein interactions between Kv2.1 and electrically silent Kv6.1 alpha-subunits were detected using two microelectrode voltage clamp and yeast two-hybrid measurements. Amino terminal portions of Kv6.1 were unable to form homomultimers but interacted specifically with amino termini of Kv2.1. Xenopus oocytes ... [more]
FEBS Lett. Dec. 09, 1996; 399(1);177-82 [Pubmed: 8980147]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| KCNA2 KCNA2 | Reconstituted Complex Reconstituted Complex An interaction is detected between purified proteins in vitro. | Low | - | BioGRID | - |
Curated By
- BioGRID