HAT1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
ACAA1
Gene Ontology Biological Process
- alpha-linolenic acid metabolic process [TAS]
- bile acid metabolic process [IMP]
- cellular lipid metabolic process [TAS]
- fatty acid beta-oxidation [IMP]
- fatty acid beta-oxidation using acyl-CoA oxidase [TAS]
- small molecule metabolic process [TAS]
- unsaturated fatty acid metabolic process [TAS]
- very long-chain fatty acid metabolic process [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Biochemical Activity (Acetylation)
An interaction is inferred from the biochemical effect of one protein upon another, for example, GTP-GDP exchange activity or phosphorylation of a substrate by a kinase. The bait protein executes the activity on the substrate hit protein. A Modification value is recorded for interactions of this type with the possible values Phosphorylation, Ubiquitination, Sumoylation, Dephosphorylation, Methylation, Prenylation, Acetylation, Deubiquitination, Proteolytic Processing, Glucosylation, Nedd(Rub1)ylation, Deacetylation, No Modification, Demethylation.
Publication
Nucleosomal DNA regulates the core-histone-binding subunit of the human Hat1 acetyltransferase.
BACKGROUND: In eukaryotic cells, newly synthesized histone H4 is acetylated at lysines 5 and 12, a transient modification erased by deacetylases shortly after deposition of histones into chromosomes. Genetic studies in Saccharomyces cerevisiae revealed that acetylation of newly synthesized histones H3 and H4 is likely to be important for maintaining cell viability; the precise biochemical function of this acetylation is ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID