BAIT
PTHLH
BDE2, HHM, PLP, PTHR, PTHRP
parathyroid hormone-like hormone
GO Process (10)
GO Function (1)
GO Component (5)
Gene Ontology Biological Process
- adenylate cyclase-activating G-protein coupled receptor signaling pathway [IDA]
- cAMP metabolic process [TAS]
- cell-cell signaling [TAS]
- epidermis development [TAS]
- female pregnancy [TAS]
- negative regulation of cell proliferation [TAS]
- negative regulation of chondrocyte differentiation [IDA]
- positive regulation of cAMP biosynthetic process [IDA]
- regulation of gene expression [IDA]
- skeletal system development [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ELAVL1
ELAV1, HUR, Hua, MelG
ELAV like RNA binding protein 1
GO Process (8)
GO Function (9)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
von Hippel-Lindau tumor suppressor gene-dependent mRNA stabilization of the survival factor parathyroid hormone-related protein in human renal cell carcinoma by the RNA-binding protein HuR.
We have shown that parathyroid hormone-related protein (PTHrP) is a survival factor for human renal cell carcinoma (RCC) and that its expression is negatively regulated by the von Hippel-Lindau (VHL) tumor suppressor gene at the level of messenger RNA (mRNA) stability, as observed for tumor growth factors (TGFs). Our goals were to analyze the alternative splicing of PTHrP mRNA in ... [more]
Carcinogenesis Mar. 01, 2009; 30(3);387-96 [Pubmed: 19056930]
Throughput
- Low Throughput
Curated By
- BioGRID