BAIT
NEK1
NY-REN-55, SRPS2, SRPS2A, SRTD6
NIMA-related kinase 1
GO Process (1)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
KIF3A
FLA10, KLP-20
kinesin family member 3A
GO Process (11)
GO Function (5)
GO Component (7)
Gene Ontology Biological Process
- ATP catabolic process [IBA]
- antigen processing and presentation of exogenous peptide antigen via MHC class II [TAS]
- blood coagulation [TAS]
- cilium assembly [ISS]
- cilium morphogenesis [IBA]
- membrane organization [TAS]
- metabolic process [IBA, TAS]
- microtubule-based movement [IBA, TAS]
- neurogenesis [IBA]
- organelle organization [TAS]
- plus-end-directed vesicle transport along microtubule [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Identification of proteins that interact with the central coiled-coil region of the human protein kinase NEK1.
NEK protein kinases are evolutionarily conserved kinases structurally related to the Aspergillus nidulans mitotic regulator NIMA. At least nine members of the NEK family in vertebrates have been described to date, but for most of them the interacting protein partners are unknown. The pleiotropic deleterious effects and the formation of kidney cysts caused by NEK1 mutation in mice emphasize its ... [more]
Biochemistry Dec. 30, 2003; 42(51);15369-76 [Pubmed: 14690447]
Throughput
- Low Throughput
Curated By
- BioGRID