BAIT
UBQLN4
A1U, A1Up, C1orf6, CIP75, UBIN, RP11-336K24.8
ubiquilin 4
GO Process (1)
GO Function (3)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SRGN
PPG, PRG, PRG1
serglycin
GO Process (11)
GO Function (1)
GO Component (5)
Gene Ontology Biological Process
- T cell secretory granule organization [ISS]
- blood coagulation [TAS]
- granzyme-mediated apoptotic signaling pathway [IDA]
- maintenance of granzyme B location in T cell secretory granule [ISS]
- maintenance of protease location in mast cell secretory granule [ISS]
- mast cell secretory granule organization [ISS]
- negative regulation of bone mineralization [IDA]
- negative regulation of cytokine secretion [ISS]
- platelet activation [TAS]
- platelet degranulation [TAS]
- protein processing [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.
Many human inherited neurodegenerative disorders are characterized by loss of balance due to cerebellar Purkinje cell (PC) degeneration. Although the disease-causing mutations have been identified for a number of these disorders, the normal functions of the proteins involved remain, in many cases, unknown. To gain insight into the function of proteins involved in PC degeneration, we developed an interaction network ... [more]
Cell May. 19, 2006; 125(4);801-14 [Pubmed: 16713569]
Throughput
- High Throughput
Curated By
- BioGRID