BAIT
UBQLN4
A1U, A1Up, C1orf6, CIP75, UBIN, RP11-336K24.8
ubiquilin 4
GO Process (1)
GO Function (3)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ROBO2
SAX3
roundabout, axon guidance receptor, homolog 2 (Drosophila)
GO Process (14)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
- apoptotic process involved in luteolysis [IEP]
- axon guidance [ISS, TAS]
- axon midline choice point recognition [ISS]
- brain development [IEP]
- cellular response to hormone stimulus [IEP]
- central nervous system development [NAS]
- homophilic cell adhesion via plasma membrane adhesion molecules [IDA]
- metanephros development [ISS]
- negative regulation of negative chemotaxis [IDA]
- negative regulation of synapse assembly [ISS]
- olfactory bulb interneuron development [ISS]
- positive regulation of axonogenesis [IDA]
- retinal ganglion cell axon guidance [ISS]
- ureteric bud development [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.
Many human inherited neurodegenerative disorders are characterized by loss of balance due to cerebellar Purkinje cell (PC) degeneration. Although the disease-causing mutations have been identified for a number of these disorders, the normal functions of the proteins involved remain, in many cases, unknown. To gain insight into the function of proteins involved in PC degeneration, we developed an interaction network ... [more]
Cell May. 19, 2006; 125(4);801-14 [Pubmed: 16713569]
Throughput
- High Throughput
Curated By
- BioGRID