Co-localization

Interaction inferred from two proteins that co-localize in the cell by indirect immunofluorescence only when in addition, if one gene is deleted, the other protein becomes mis-localized. Also includes co-dependent association of proteins with promoter DNA in chromatin immunoprecipitation experiments.

Publication

Interaction of Bap31 and MHC class I molecules and their traffic out of the endoplasmic reticulum.

Abe F, Van Prooyen N, Ladasky JJ, Edidin M

The endoplasmic reticulum (ER) protein Bap31 associates with nascent class I MHC molecules. It appears to mediate the export of class I MHC molecules from the ER and may also be involved in their quality control. In this study, we use Foerster resonance energy transfer and quantitative fluorescence imaging to show that in human, HeLa cells, Bap31 clusters with MHC ... [more]

J. Immunol. Apr. 15, 2009; 182(8);4776-83 [Pubmed: 19342655]

Throughput

  • Low Throughput

Curated By

  • BioGRID