BAIT

TOR1A

DQ2, Dyt1, torsinA, RP23-221O14.9
torsin family 1, member A (torsin A)
Mus musculus
PREY

KLHL14

6330403N15Rik, AI785250, printor
kelch-like 14
GO Process (0)
GO Function (1)
GO Component (3)

Gene Ontology Molecular Function

Mus musculus

Affinity Capture-Western

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.

Publication

Printor, a novel torsinA-interacting protein implicated in dystonia pathogenesis.

Giles LM, Li L, Chin LS

Early onset generalized dystonia (DYT1) is an autosomal dominant neurological disorder caused by deletion of a single glutamate residue (torsinA DeltaE) in the C-terminal region of the AAA(+) (ATPases associated with a variety of cellular activities) protein torsinA. The pathogenic mechanism by which torsinA DeltaE mutation leads to dystonia remains unknown. Here we report the identification and characterization of a ... [more]

J. Biol. Chem. Aug. 07, 2009; 284(32);21765-75 [Pubmed: 19535332]

Throughput

  • Low Throughput

Curated By

  • BioGRID