ABI1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
WASF2
Gene Ontology Biological Process
- Rac protein signal transduction [IMP]
- actin cytoskeleton organization [IMP]
- actin filament-based movement [IMP]
- ameboidal-type cell migration [IMP]
- angiogenesis [IMP]
- cellular component movement [IMP]
- endocytosis [IDA]
- lamellipodium assembly [IMP]
- lamellipodium morphogenesis [IMP]
- megakaryocyte development [IMP]
- negative regulation of stress fiber assembly [ISO]
- positive regulation of lamellipodium assembly [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization.
BCR-ABL1 is a fusion tyrosine kinase, which causes multiple types of leukemia. We used an integrated proteomic approach that includes label-free quantitative protein complex and phosphorylation profiling by mass spectrometry to systematically characterize the proximal signaling network of this oncogenic kinase. The proximal BCR-ABL1 signaling network shows a modular and layered organization with an inner core of three leukemia transformation-relevant ... [more]
Throughput
- Low Throughput
Additional Notes
- table S2.
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| WASF2 ABI1 | Co-fractionation Co-fractionation Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex. | High | 0.97 | BioGRID | 2666371 |
Curated By
- BioGRID