BAIT
DOK1
AW557123, p62DOK
docking protein 1
GO Process (4)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Mus musculus
PREY
PHGDH
3-PGDH, 3PGDH, 4930479N23, A10, PGAD, PGD, PGDH, SERA
3-phosphoglycerate dehydrogenase
GO Process (14)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
- G1 to G0 transition [IMP]
- L-serine metabolic process [IMP]
- gamma-aminobutyric acid metabolic process [IMP]
- glial cell development [IMP]
- glutamine metabolic process [IMP]
- glycine metabolic process [IMP]
- neural tube development [IMP]
- neurogenesis [IMP]
- neuron projection development [IMP]
- oxidation-reduction process [ISO]
- regulation of gene expression [IMP]
- spinal cord development [IMP]
- taurine metabolic process [IMP]
- threonine metabolic process [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization.
BCR-ABL1 is a fusion tyrosine kinase, which causes multiple types of leukemia. We used an integrated proteomic approach that includes label-free quantitative protein complex and phosphorylation profiling by mass spectrometry to systematically characterize the proximal signaling network of this oncogenic kinase. The proximal BCR-ABL1 signaling network shows a modular and layered organization with an inner core of three leukemia transformation-relevant ... [more]
Oncogene Nov. 04, 2010; 29(44);5895-910 [Pubmed: 20697350]
Throughput
- Low Throughput
Additional Notes
- table S2.
Curated By
- BioGRID