BAIT

NEDD9

Cas-L, CasL, HEF1, MEF1, Nedd-9, p105
neural precursor cell expressed, developmentally down-regulated gene 9
GO Process (0)
GO Function (0)
GO Component (2)

Gene Ontology Cellular Component

Mus musculus
PREY

CRK

Crk-I, Crk-II, Crk-III, Crk3, CrkIII, Crko, c-Crk, p38, RP23-136K12.1
v-crk sarcoma virus CT10 oncogene homolog (avian)
Mus musculus

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization.

Titz B, Low T, Komisopoulou E, Chen SS, Rubbi L, Graeber TG

BCR-ABL1 is a fusion tyrosine kinase, which causes multiple types of leukemia. We used an integrated proteomic approach that includes label-free quantitative protein complex and phosphorylation profiling by mass spectrometry to systematically characterize the proximal signaling network of this oncogenic kinase. The proximal BCR-ABL1 signaling network shows a modular and layered organization with an inner core of three leukemia transformation-relevant ... [more]

Oncogene Nov. 04, 2010; 29(44);5895-910 [Pubmed: 20697350]

Throughput

  • Low Throughput

Additional Notes

  • table S2.

Curated By

  • BioGRID