BAIT
HINFP
HiNF-P, MIZF, ZNF743
histone H4 transcription factor
GO Process (13)
GO Function (7)
GO Component (4)
Gene Ontology Biological Process
- DNA damage checkpoint [IMP]
- DNA repair [IMP]
- G1/S transition of mitotic cell cycle [IMP]
- establishment of protein localization [IMP]
- in utero embryonic development [ISS]
- myoblast differentiation [IMP]
- negative regulation of gene expression [IMP]
- negative regulation of transcription, DNA-templated [IDA]
- positive regulation of gene expression [IMP]
- positive regulation of transcription, DNA-templated [IDA]
- regulation of gene expression [IMP]
- regulation of transcription involved in G1/S transition of mitotic cell cycle [IMP]
- regulation of transcription, DNA-templated [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ZNHIT1
CG1I, ZNFN4A1
zinc finger, HIT-type containing 1
GO Process (2)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
The interactome of the histone gene regulatory factor HiNF-P suggests novel cell cycle related roles in transcriptional control and RNA processing.
HiNF-P is a recently identified histone H4 subtype specific transcriptional regulator that associates with the conserved cell cycle control element in the proximal promoter regions of histone H4 genes. HiNF-P interacts with the global histone gene regulator and direct cyclin E/CDK2 substrate p220(NPAT) to potently upregulate histone H4 gene transcription at the G1/S phase transition in response to cyclin E/CDK2 ... [more]
J. Cell. Biochem. Sep. 01, 2007; 102(1);136-48 [Pubmed: 17577209]
Throughput
- High Throughput
Curated By
- BioGRID