Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.

Publication

Dynamic association of proteasomal machinery with the centrosome.

Wigley WC, Fabunmi RP, Lee MG, Marino CR, Muallem S, DeMartino GN, Thomas PJ

Although the number of pathologies known to arise from the inappropriate folding of proteins continues to grow, mechanisms underlying the recognition and ultimate disposition of misfolded polypeptides remain obscure. For example, how and where such substrates are identified and processed is unknown. We report here the identification of a specific subcellular structure in which, under basal conditions, the 20S proteasome, ... [more]

J. Cell Biol. May. 03, 1999; 145(3);481-90 [Pubmed: 10225950]

Throughput

Low Throughput

Curated By

BioGRID

Interaction Summary

TUBG1

Gene Ontology Biological Process

Gene Ontology Molecular Function

protein binding [IPI]structural constituent of cytoskeleton [TAS]

Gene Ontology Cellular Component

HSPA4