Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

UCHL1 regulates ubiquitination and recycling of the neural cell adhesion molecule NCAM.

Wobst H, Foerster S, Laurini C, Sekulla A, Dreiseidler M, Hoehfeld J, Schmitz B, Diestel S

The neural cell adhesion molecule NCAM is involved in neural development and in plasticity in the adult brain. NCAM140 and NCAM180 isoforms are transmembrane proteins with cytoplasmic domains which differ only in an alternatively spliced exon in the NCAM180 isoform. Both isoforms can interact with several extracellular and cytoplasmic molecules mediating NCAM-dependent functions. Most identified intracellular interaction partners bind to ... [more]

FEBS J. Oct. 13, 2012; 0(0); [Pubmed: 23061666]

Throughput

  • Low Throughput

Curated By

  • BioGRID