Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

Interactive sequences in the stress protein and molecular chaperone human alphaB crystallin recognize and modulate the assembly of filaments.

Ghosh JG, Houck SA, Clark JI

Molecular chaperones including the small heat shock proteins, alphaB crystallin and sHSP27 participate in the assembly, disassembly, and reorganization of the cytoskeleton during cell development and differentiation. While alphaB crystallin and sHSP27 stabilize and modulate filament assembly and re-organization, the sequences and structural domains mediating interactions between these proteins and filaments are unknown. It is important to define these interactive ... [more]

Int. J. Biochem. Cell Biol. Jun. 26, 2007; 39(10);1804-15 [Pubmed: 17590381]

Throughput

  • Low Throughput

Curated By

  • BioGRID