BAIT
NDN
AI528698, Peg6
necdin
GO Process (17)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
- axon extension [IMP]
- axonal fasciculation [IMP]
- axonogenesis [IMP]
- cellular calcium ion homeostasis [TAS]
- central nervous system development [IMP]
- genetic imprinting [IMP]
- glial cell migration [IMP]
- multicellular organismal homeostasis [IMP]
- neuron development [IMP]
- neuron migration [IMP]
- neurotrophin TRK receptor signaling pathway [IMP]
- post-embryonic development [IMP]
- regulation of cell growth [TAS]
- regulation of transcription, DNA-templated [IGI]
- respiratory gaseous exchange [IMP]
- respiratory system process [IMP]
- sensory perception of pain [IMP]
Gene Ontology Molecular Function
Mus musculus
PREY
HAP1
HAP-1, RP23-392I3.11-001
huntingtin-associated protein 1
GO Process (19)
GO Function (6)
GO Component (11)
Gene Ontology Biological Process
- anterograde axon cargo transport [IMP, ISO]
- cerebellum development [IMP]
- hypothalamus cell differentiation [IMP]
- negative regulation of beta-amyloid formation [ISO]
- neuron projection development [ISO]
- neurotrophin TRK receptor signaling pathway [IMP]
- positive regulation of epidermal growth factor receptor signaling pathway [ISO]
- positive regulation of inclusion body assembly [ISO]
- positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [IMP, ISO]
- positive regulation of neurogenesis [IMP]
- positive regulation of neuron projection development [ISO]
- positive regulation of neurotrophin production [ISO]
- positive regulation of nonmotile primary cilium assembly [IMP]
- positive regulation of synaptic transmission, GABAergic [ISO]
- protein localization [ISO]
- regulation of exocytosis [IMP]
- regulation of organelle transport along microtubule [IMP]
- retrograde axon cargo transport [ISO]
- vesicle transport along microtubule [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Functional consequences of necdin nucleocytoplasmic localization.
Necdin, a MAGE family protein expressed primarily in the nervous system, has been shown to interact with both nuclear and cytoplasmic proteins, but the mechanism of its nucleocytoplasmic transport are unknown.We carried out a large-scale interaction screen using necdin as a bait in the yeast RRS system, and found a wide range of potential interactors with different subcellular localizations, including ... [more]
PLoS ONE Mar. 24, 2012; 7(3);e33786 [Pubmed: 22442722]
Throughput
- High Throughput
Curated By
- BioGRID