BAIT
NDN
AI528698, Peg6
necdin
GO Process (17)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
- axon extension [IMP]
- axonal fasciculation [IMP]
- axonogenesis [IMP]
- cellular calcium ion homeostasis [TAS]
- central nervous system development [IMP]
- genetic imprinting [IMP]
- glial cell migration [IMP]
- multicellular organismal homeostasis [IMP]
- neuron development [IMP]
- neuron migration [IMP]
- neurotrophin TRK receptor signaling pathway [IMP]
- post-embryonic development [IMP]
- regulation of cell growth [TAS]
- regulation of transcription, DNA-templated [IGI]
- respiratory gaseous exchange [IMP]
- respiratory system process [IMP]
- sensory perception of pain [IMP]
Gene Ontology Molecular Function
Mus musculus
PREY
CAMK1
AI505105, CaMKIalpha, D6Ertd263e
calcium/calmodulin-dependent protein kinase I
GO Process (12)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
- nucleocytoplasmic transport [IDA, IGI]
- positive regulation of dendritic spine development [ISO]
- positive regulation of muscle cell differentiation [ISO]
- positive regulation of neuron projection development [ISO]
- positive regulation of protein export from nucleus [IDA]
- positive regulation of protein serine/threonine kinase activity [ISO]
- positive regulation of synapse structural plasticity [ISO]
- protein phosphorylation [IDA, IGI, ISO]
- regulation of muscle cell differentiation [ISO]
- regulation of protein binding [ISO]
- regulation of protein localization [ISO]
- signal transduction [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- cell [IGI]
- intracellular [IGI]
Mus musculus
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Functional consequences of necdin nucleocytoplasmic localization.
Necdin, a MAGE family protein expressed primarily in the nervous system, has been shown to interact with both nuclear and cytoplasmic proteins, but the mechanism of its nucleocytoplasmic transport are unknown.We carried out a large-scale interaction screen using necdin as a bait in the yeast RRS system, and found a wide range of potential interactors with different subcellular localizations, including ... [more]
PLoS ONE Mar. 24, 2012; 7(3);e33786 [Pubmed: 22442722]
Throughput
- High Throughput
Curated By
- BioGRID