BAIT
NDN
AI528698, Peg6
necdin
GO Process (17)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
- axon extension [IMP]
- axonal fasciculation [IMP]
- axonogenesis [IMP]
- cellular calcium ion homeostasis [TAS]
- central nervous system development [IMP]
- genetic imprinting [IMP]
- glial cell migration [IMP]
- multicellular organismal homeostasis [IMP]
- neuron development [IMP]
- neuron migration [IMP]
- neurotrophin TRK receptor signaling pathway [IMP]
- post-embryonic development [IMP]
- regulation of cell growth [TAS]
- regulation of transcription, DNA-templated [IGI]
- respiratory gaseous exchange [IMP]
- respiratory system process [IMP]
- sensory perception of pain [IMP]
Gene Ontology Molecular Function
Mus musculus
PREY
CHMP4B
2010012F05Rik, C76846, Snf7-2, RP23-29D15.3
charged multivesicular body protein 4B
GO Process (8)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
- negative regulation of autophagic vacuole assembly [ISO]
- negative regulation of neuron death [ISO]
- positive regulation of viral release from host cell [ISO]
- posttranslational protein targeting to membrane [ISO]
- protein homooligomerization [ISO]
- regulation of viral process [ISO]
- ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway [ISO]
- viral budding via host ESCRT complex [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Functional consequences of necdin nucleocytoplasmic localization.
Necdin, a MAGE family protein expressed primarily in the nervous system, has been shown to interact with both nuclear and cytoplasmic proteins, but the mechanism of its nucleocytoplasmic transport are unknown.We carried out a large-scale interaction screen using necdin as a bait in the yeast RRS system, and found a wide range of potential interactors with different subcellular localizations, including ... [more]
PLoS ONE Mar. 24, 2012; 7(3);e33786 [Pubmed: 22442722]
Throughput
- High Throughput
Curated By
- BioGRID