BAIT
ADAM15
MDC15, RP11-540D14.1
ADAM metallopeptidase domain 15
GO Process (11)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- apoptotic process [IDA]
- cell-matrix adhesion [TAS]
- extracellular matrix disassembly [TAS]
- extracellular matrix organization [TAS]
- innate immune response [IDA]
- integrin-mediated signaling pathway [IMP]
- negative regulation of cell growth [IMP]
- negative regulation of cell migration [IMP]
- negative regulation of cell-matrix adhesion [IMP]
- negative regulation of receptor binding [IMP]
- protein kinase C signaling [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
YES1
HsT441, P61-YES, Yes, c-yes
YES proto-oncogene 1, Src family tyrosine kinase
GO Process (12)
GO Function (6)
GO Component (7)
Gene Ontology Biological Process
- Fc-gamma receptor signaling pathway involved in phagocytosis [TAS]
- T cell costimulation [TAS]
- blood coagulation [TAS]
- cell differentiation [IBA]
- cellular protein modification process [TAS]
- cellular response to peptide hormone stimulus [IBA]
- innate immune response [IBA, TAS]
- leukocyte migration [TAS]
- peptidyl-tyrosine autophosphorylation [IBA]
- regulation of cell proliferation [IBA]
- regulation of vascular permeability [TAS]
- transmembrane receptor protein tyrosine kinase signaling pathway [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Identification of preferred protein interactions by phage-display of the human Src homology-3 proteome.
We have determined the human genome to contain 296 different Src homology-3 (SH3) domains and cloned them into a phage-display vector. This provided a powerful and unbiased system for simultaneous assaying of the complete human SH3 proteome for the strongest binding to target proteins of interest, without the limitations posed by short linear peptide ligands or confounding variables of more ... [more]
EMBO Rep. Feb. 01, 2006; 7(2);186-91 [Pubmed: 16374509]
Throughput
- Low Throughput
Curated By
- BioGRID