PRKCG
Gene Ontology Biological Process
- chemosensory behavior [ISO]
- innervation [ISO]
- intracellular signal transduction [NAS]
- learning or memory [IEP]
- negative regulation of neuron apoptotic process [IMP]
- negative regulation of proteasomal protein catabolic process [ISO, ISS]
- negative regulation of protein catabolic process [ISO]
- negative regulation of protein ubiquitination [ISO, ISS]
- phosphorylation [ISO]
- positive regulation of mismatch repair [ISO]
- protein autophosphorylation [IDA]
- regulation of circadian rhythm [ISO, ISS]
- regulation of response to food [ISO, ISS]
- response to morphine [ISO, ISS]
- response to pain [ISO, ISS]
- synaptic transmission [ISO, NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
STXBP1
Gene Ontology Biological Process
- axon target recognition [ISO]
- exocytosis [ISO]
- long term synaptic depression [ISO]
- negative regulation of neuron apoptotic process [ISO]
- negative regulation of synaptic transmission, GABAergic [ISO]
- neuromuscular synaptic transmission [ISO]
- neurotransmitter secretion [ISO]
- platelet aggregation [ISO]
- platelet degranulation [ISO]
- positive regulation of calcium ion-dependent exocytosis [ISO]
- positive regulation of exocytosis [IMP]
- protein localization to plasma membrane [ISO]
- protein stabilization [IDA]
- regulation of synaptic vesicle priming [IMP]
- synaptic vesicle maturation [ISO]
- vesicle docking involved in exocytosis [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Biochemical Activity (Phosphorylation)
An interaction is inferred from the biochemical effect of one protein upon another, for example, GTP-GDP exchange activity or phosphorylation of a substrate by a kinase. The bait protein executes the activity on the substrate hit protein. A Modification value is recorded for interactions of this type with the possible values Phosphorylation, Ubiquitination, Sumoylation, Dephosphorylation, Methylation, Prenylation, Acetylation, Deubiquitination, Proteolytic Processing, Glucosylation, Nedd(Rub1)ylation, Deacetylation, No Modification, Demethylation.
Publication
Phosphorylation of Munc-18/n-Sec1/rbSec1 by protein kinase C: its implication in regulating the interaction of Munc-18/n-Sec1/rbSec1 with syntaxin.
Munc-18/n-Sec1/rbSec1 interacts with syntaxin and this interaction inhibits the association of vesicle-associated membrane protein (VAMP)/synaptobrevin and synaptosomal-associated protein of 25 kDa (SNAP-25) with syntaxin. Syntaxin, VAMP, and SNAP-25 serve as soluble N-ethylmaleimide-sensitive fusion protein attachment protein (SNAP) receptors essential for docking and/or fusion of synaptic vesicles with the presynaptic plasma membrane. Genetic analyses in yeast, Caenorhabditis elegans, and Drosophila suggest ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID