BAIT
TOP1
TOPI, RP3-511B24.1
topoisomerase (DNA) I
GO Process (9)
GO Function (6)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
TARBP2
LOQS, TRBP, TRBP1, TRBP2
TAR (HIV-1) RNA binding protein 2
GO Process (11)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
- gene expression [TAS]
- miRNA loading onto RISC involved in gene silencing by miRNA [IDA]
- negative regulation of defense response to virus by host [IDA]
- negative regulation of protein kinase activity [TAS]
- positive regulation of viral genome replication [IDA]
- pre-miRNA processing [IDA]
- production of siRNA involved in RNA interference [IDA]
- regulation of transcription from RNA polymerase II promoter [TAS]
- regulation of transcription, DNA-templated [TAS]
- regulation of viral transcription [IDA]
- targeting of mRNA for destruction involved in RNA interference [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Protein-peptide
An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.
Publication
Potential protein partners for the N-terminal domain of human topoisomerase I revealed by phage display.
Phage display procedure was applied to the N-terminal domain of human topoisomerase I. The consensus sequence identified for clones binding to the N-terminal domain was found in 35 human proteins that are either permanently or temporarily located in the nucleus. They are in majority involved in the DNA repair, transcription, RNA metabolism or cell cycle control. Four of identified proteins: ... [more]
Mol. Biol. Rep. Dec. 01, 2002; 29(4);347-52 [Pubmed: 12549820]
Throughput
- Low Throughput
Additional Notes
- table 1.
Curated By
- BioGRID