LMAN1
Gene Ontology Biological Process
- ER to Golgi vesicle-mediated transport [TAS]
- Golgi organization [IMP]
- blood coagulation [TAS]
- cellular protein metabolic process [TAS]
- early endosome to Golgi transport [IMP]
- positive regulation of organelle organization [IMP]
- post-translational protein modification [TAS]
- protein N-linked glycosylation via asparagine [TAS]
- protein exit from endoplasmic reticulum [IMP]
- protein folding [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
DNAJC7
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Protein interaction profiling of the p97 adaptor UBXD1 points to a role for the complex in modulating ERGIC-53 trafficking.
UBXD1 is a member of the poorly understood subfamily of p97 adaptors that do not harbor a ubiquitin association domain or bind ubiquitin-modified proteins. Of clinical importance, p97 mutants found in familial neurodegenerative conditions Inclusion Body Myopathy Paget's disease of the bone and/or Frontotemporal Dementia and Amyotrophic Lateral Sclerosis are defective at interacting with UBXD1, indicating that functions regulated by ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| LMAN1 DNAJC7 | Proximity Label-MS Proximity Label-MS An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods. | High | 8.06 | BioGRID | 2994361 |
Curated By
- BioGRID