BAIT
LIPC
AI256194, HL, Hpl
lipase, hepatic
GO Process (23)
GO Function (14)
GO Component (5)
Gene Ontology Biological Process
- cholesterol homeostasis [IGI, ISO]
- cholesterol metabolic process [IGI]
- cholesterol transport [IMP]
- chylomicron remnant clearance [ISO]
- chylomicron remodeling [ISO]
- fatty acid biosynthetic process [ISO]
- fatty acid metabolic process [ISO]
- glycerophospholipid catabolic process [ISO]
- heparan sulfate proteoglycan biosynthetic process [ISO]
- high-density lipoprotein particle remodeling [ISO]
- low-density lipoprotein particle clearance [ISO]
- low-density lipoprotein particle remodeling [ISO]
- neutral lipid catabolic process [ISO]
- phosphatidic acid metabolic process [ISO]
- phosphatidylcholine metabolic process [ISO]
- phosphatidylethanolamine metabolic process [ISO]
- phosphatidylserine metabolic process [ISO]
- protein oligomerization [ISO]
- regulation of plasma lipoprotein particle levels [ISO]
- triglyceride catabolic process [ISO]
- triglyceride homeostasis [ISO]
- triglyceride metabolic process [ISO]
- very-low-density lipoprotein particle remodeling [ISO]
Gene Ontology Molecular Function- acylglycerol lipase activity [ISO]
- apolipoprotein binding [ISO]
- carboxylic ester hydrolase activity [ISO]
- chylomicron binding [ISO]
- heparan sulfate proteoglycan binding [ISO]
- heparin binding [ISO]
- lipase activity [IDA]
- lipid binding [ISO]
- low-density lipoprotein particle binding [ISO]
- lysophospholipase activity [ISO]
- phosphatidylcholine 1-acylhydrolase activity [ISO]
- protein binding [IPI]
- transferase activity, transferring acyl groups [ISO]
- triglyceride lipase activity [ISO]
- acylglycerol lipase activity [ISO]
- apolipoprotein binding [ISO]
- carboxylic ester hydrolase activity [ISO]
- chylomicron binding [ISO]
- heparan sulfate proteoglycan binding [ISO]
- heparin binding [ISO]
- lipase activity [IDA]
- lipid binding [ISO]
- low-density lipoprotein particle binding [ISO]
- lysophospholipase activity [ISO]
- phosphatidylcholine 1-acylhydrolase activity [ISO]
- protein binding [IPI]
- transferase activity, transferring acyl groups [ISO]
- triglyceride lipase activity [ISO]
Gene Ontology Cellular Component
Mus musculus
PREY
SLC25A5
Ant2, RP23-286I5.1
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5
GO Process (2)
GO Function (1)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Hepatic lipase maturation: a partial proteome of interacting factors.
Tandem affinity purification (TAP) has been used to isolate proteins that interact with human hepatic lipase (HL) during its maturation in Chinese hamster ovary cells. Using mass spectrometry and Western blotting, we identified 28 proteins in HL-TAP isolated complexes, 16 of which localized to the endoplasmic reticulum (ER), the site of HL folding and assembly. Of the 12 remaining proteins ... [more]
J. Lipid Res. Jun. 01, 2009; 50(6);1173-84 [Pubmed: 19136429]
Throughput
- High Throughput
Curated By
- BioGRID