BAIT
MAPRE1
EB1
microtubule-associated protein, RP/EB family, member 1
GO Process (5)
GO Function (4)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
TUBB
CDCBM6, M40, OK/SW-cl.56, TUBB1, TUBB5, DAAP-285E11.4
tubulin, beta class I
GO Process (8)
GO Function (4)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Microtubule-binding sites of the CH domain of EB1 and its autoinhibition revealed by NMR.
End-binding protein 1 (EB1) is one of the best studied plus-end tracking proteins. It is known that EB1 specifically binds the plus ends of microtubules (MTs) and promotes MT growth. EB1 activity is thought to be autoinhibited by an intramolecular interaction. Recent cryo-EM analyses showed that the CH domain of Mal3p (Schizosaccharomycespombe EB1 homolog) binds to GMPCPP-MT (Sandblad, L. Cell ... [more]
Biochim. Biophys. Acta Nov. 02, 2012; 0(0); [Pubmed: 23128140]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| TUBB MAPRE1 | Reconstituted Complex Reconstituted Complex An interaction is detected between purified proteins in vitro. | Low | - | BioGRID | - |
Curated By
- BioGRID