BAIT
CUL3
AI467304, AW146203, mKIAA0617
cullin 3
GO Process (26)
GO Function (6)
GO Component (8)
Gene Ontology Biological Process
- COPII vesicle coating [ISO]
- ER to Golgi vesicle-mediated transport [ISO]
- Wnt signaling pathway [IDA]
- cell migration [ISO]
- cell morphogenesis [IMP]
- embryonic cleavage [IMP]
- fibroblast apoptotic process [IMP]
- gastrulation [IMP]
- in utero embryonic development [IMP]
- integrin-mediated signaling pathway [IMP]
- liver morphogenesis [IMP]
- mitotic cell cycle [IMP]
- mitotic metaphase plate congression [ISO]
- negative regulation of Rho protein signal transduction [ISO]
- negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation [ISS]
- negative regulation of transcription from RNA polymerase II promoter [IMP]
- positive regulation of cytokinesis [ISO]
- positive regulation of mitotic metaphase/anaphase transition [ISO]
- proteasome-mediated ubiquitin-dependent protein catabolic process [IGI, ISO]
- protein monoubiquitination [ISO]
- protein polyubiquitination [ISO]
- protein ubiquitination [ISO]
- regulation of transcription from RNA polymerase II promoter [IGI]
- stem cell division [IMP]
- stress fiber assembly [ISO]
- trophectodermal cellular morphogenesis [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
RORC
Nr1f3, RORgamma, TOR, Thor
RAR-related orphan receptor gamma
GO Process (22)
GO Function (7)
GO Component (1)
Gene Ontology Biological Process
- Peyer's patch development [IMP]
- T cell differentiation in thymus [IMP]
- T-helper 17 cell differentiation [IDA, IMP]
- T-helper cell differentiation [IMP]
- adipose tissue development [IMP]
- alpha-beta T cell differentiation [IMP]
- cell differentiation [IMP]
- cellular response to sterol [ISO]
- circadian regulation of gene expression [IMP]
- lymph node development [IMP]
- mucosal-associated lymphoid tissue development [IMP]
- negative regulation of thymocyte apoptotic process [IMP]
- positive regulation of circadian rhythm [IDA]
- positive regulation of transcription, DNA-templated [IDA]
- protein phosphorylation [IMP]
- regulation of fat cell differentiation [IMP]
- regulation of gamma-delta T cell differentiation [IDA]
- regulation of glucose metabolic process [IMP]
- regulation of steroid metabolic process [IMP]
- regulation of transcription involved in cell fate commitment [IDA]
- regulation of transcription, DNA-templated [ISO]
- xenobiotic metabolic process [IMP]
Gene Ontology Molecular Function
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs.
The differentiation of several T- and B-cell effector programs in the immune system is directed by signature transcription factors that induce rapid epigenetic remodelling. Here we report that promyelocytic leukaemia zinc finger (PLZF), the BTB-zinc finger (BTB-ZF) transcription factor directing the innate-like effector program of natural killer T-cell thymocytes, is prominently associated with cullin 3 (CUL3), an E3 ubiquitin ligase ... [more]
Nature Nov. 22, 2012; 491(7425);618-21 [Pubmed: 23086144]
Throughput
- Low Throughput
Curated By
- BioGRID