BAIT
SSTR1
Gpcrrna
somatostatin receptor 1
GO Process (13)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [ISO]
- G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger [IBA]
- T cell differentiation [NAS]
- cellular response to estradiol stimulus [IEP]
- cerebellum development [IEP]
- forebrain development [IEP]
- glutamate receptor signaling pathway [ISO]
- negative regulation of cell proliferation [IBA]
- neuropeptide signaling pathway [IBA, ISO]
- response to starvation [IEP]
- somatostatin signaling pathway [IMP, ISO]
- spermatogenesis [IEP]
- synaptic transmission [IBA, ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
PRMT5
HRMT1L5, IBP72, JBP1, SKB1, SKB1Hs
protein arginine methyltransferase 5
GO Process (13)
GO Function (7)
GO Component (4)
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- cell proliferation [TAS]
- circadian regulation of gene expression [ISS]
- endothelial cell activation [IMP]
- gene expression [TAS]
- histone H4-R3 methylation [ISS, NAS]
- ncRNA metabolic process [TAS]
- peptidyl-arginine N-methylation [IDA]
- peptidyl-arginine methylation [IMP]
- peptidyl-arginine methylation, to symmetrical-dimethyl arginine [IMP]
- regulation of mitosis [TAS]
- regulation of transcription, DNA-templated [IBA]
- spliceosomal snRNP assembly [IMP, TAS]
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Interaction of the somatostatin receptor subtype 1 with the human homolog of the Shk1 kinase-binding protein from yeast.
Interaction between the C terminus of a G-protein-coupled receptor and intracellular constituents may represent a crucial step in regulating signal transduction. To identify potential interacting candidates the C terminus of the somatostatin receptor subtype 1 was used as bait in a yeast two hybrid screen of a human brain cDNA library. We identified the human Skb1 sequence (Skb1Hs) as interacting ... [more]
J. Biol. Chem. Mar. 31, 2000; 275(13);9557-62 [Pubmed: 10734105]
Throughput
- Low Throughput
Curated By
- BioGRID