BAIT
MUG33
SPCC1739.10
Tea1-interacting protein involved in exocytosis
GO Process (2)
GO Function (0)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Schizosaccharomyces pombe (972h)
PREY
MYO52
SPCC1919.10c
myosin type V
GO Process (8)
GO Function (1)
GO Component (7)
Gene Ontology Biological Process
- actin filament bundle organization [IMP]
- actin filament bundle retrograde transport [IMP]
- cellular protein localization [IMP]
- establishment or maintenance of cell polarity regulating cell shape [IMP]
- formin-nucleated actin cable assembly [IMP]
- mitotic cytokinesis [IMP]
- protein localization to cell tip [IMP]
- vesicle transport along actin filament [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Schizosaccharomyces pombe (972h)
Synthetic Lethality
A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition.
Publication
Characterization of Mug33 reveals complementary roles for actin cable-dependent transport and exocyst regulators in fission yeast exocytosis.
Although endocytosis and exocytosis have been extensively studied in budding yeast, there have been relatively few investigations of these complex processes in the fission yeast Schizosaccharomyces pombe. Here we identify and characterize fission yeast Mug33, a novel Tea1-interacting protein, and show that Mug33 is involved in exocytosis. Mug33 is a Sur7/PalI-family transmembrane protein that localizes to the plasma membrane at ... [more]
J. Cell. Sci. Jul. 01, 2011; 124(0);2187-99 [Pubmed: 21652630]
Throughput
- Low Throughput
Ontology Terms
- phenotype: inviable (APO:0000112)
Curated By
- BioGRID