EXO70
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
FOR3
Gene Ontology Biological Process
- actin filament bundle assembly [IMP]
- actin filament organization [IMP]
- actin nucleation [ISM]
- activation of bipolar cell growth [IMP]
- establishment or maintenance of cell polarity regulating cell shape [IMP]
- microtubule cytoskeleton organization [IGI]
- mitotic actomyosin contractile ring assembly [IGI]
- protein localization to actin cytoskeleton [IMP]
- regulation of filamentous growth [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Phenotypic Enhancement
A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene.
Publication
Characterization of Mug33 reveals complementary roles for actin cable-dependent transport and exocyst regulators in fission yeast exocytosis.
Although endocytosis and exocytosis have been extensively studied in budding yeast, there have been relatively few investigations of these complex processes in the fission yeast Schizosaccharomyces pombe. Here we identify and characterize fission yeast Mug33, a novel Tea1-interacting protein, and show that Mug33 is involved in exocytosis. Mug33 is a Sur7/PalI-family transmembrane protein that localizes to the plasma membrane at ... [more]
Throughput
- Low Throughput
Ontology Terms
- phenotype: protein secretion (APO:0000078)
Additional Notes
- exocytosis of acid phosphatase is greatly reduced in double mutant but normal in single mutants
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| FOR3 EXO70 | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | BioGRID | 482906 | |
| FOR3 EXO70 | Synthetic Growth Defect Synthetic Growth Defect A genetic interaction is inferred when mutations in separate genes, each of which alone causes a minimal phenotype, result in a significant growth defect under a given condition when combined in the same cell. | Low | - | BioGRID | 736880 | |
| FOR3 EXO70 | Synthetic Lethality Synthetic Lethality A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition. | Low | - | BioGRID | 482903 |
Curated By
- BioGRID