SEC8
Gene Ontology Biological Process
Gene Ontology Molecular Function
FOR3
Gene Ontology Biological Process
- actin filament bundle assembly [IMP]
- actin filament organization [IMP]
- actin nucleation [ISM]
- activation of bipolar cell growth [IMP]
- establishment or maintenance of cell polarity regulating cell shape [IMP]
- microtubule cytoskeleton organization [IGI]
- mitotic actomyosin contractile ring assembly [IGI]
- protein localization to actin cytoskeleton [IMP]
- regulation of filamentous growth [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Synthetic Growth Defect
A genetic interaction is inferred when mutations in separate genes, each of which alone causes a minimal phenotype, result in a significant growth defect under a given condition when combined in the same cell.
Publication
Pob1 Ensures Cylindrical Cell Shape by Coupling Two Distinct Rho Signaling Events during Secretory Vesicle Targeting.
Proper cell morphogenesis requires the coordination of cell polarity, cytoskeletal organization, and vesicle trafficking. The Schizosaccharomyces pombe mutant pob1-664 has a curious lemon-like shape, the basis of which is not understood. Here we found abundant vesicle accumulation in these cells, suggesting that Pob1 plays a role in vesicle trafficking. We identified Rho3 as a multi-copy suppressor of this phenotype. Because ... [more]
Throughput
- Low Throughput
Ontology Terms
- phenotype: vegetative growth (APO:0000106)
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| FOR3 SEC8 | Phenotypic Enhancement Phenotypic Enhancement A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene. | Low | - | BioGRID | 482896 | |
| FOR3 SEC8 | Synthetic Lethality Synthetic Lethality A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition. | Low | - | BioGRID | 482901 | |
| SEC8 FOR3 | Synthetic Lethality Synthetic Lethality A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition. | Low | - | BioGRID | 736876 |
Curated By
- BioGRID