BAIT

PPIF

CYP3, CyP-M, Cyp-D, CypD, RP11-342M3.4

peptidylprolyl isomerase F

GO Process (15)

GO Function (2)

GO Component (3)

Gene Ontology Biological Process

cellular response to arsenic-containing substance [ISS]

cellular response to calcium ion [ISS]

cellular response to hydrogen peroxide [IMP]

negative regulation of ATPase activity [ISS]

negative regulation of apoptotic process [IDA]

negative regulation of intrinsic apoptotic signaling pathway [IMP]

negative regulation of oxidative phosphorylation [ISS]

negative regulation of oxidative phosphorylation uncoupler activity [ISS]

negative regulation of release of cytochrome c from mitochondria [IDA]

positive regulation of release of cytochrome c from mitochondria [ISS]

protein peptidyl-prolyl isomerization [IBA]

regulation of mitochondrial membrane permeability [ISS]

regulation of mitochondrial membrane permeability involved in programmed necrotic cell death [IMP]

regulation of proton-transporting ATPase activity, rotational mechanism [ISS]

response to ischemia [ISS]

Gene Ontology Molecular Function

peptidyl-prolyl cis-trans isomerase activity [IBA]
protein binding [IPI]

Gene Ontology Cellular Component

mitochondrial matrix [IBA]

mitochondrial proton-transporting ATP synthase complex [ISS]

CRISPR Database OMIM VEGA HGNC Alliance of Genome Resources Entrez Gene RefSeq UniprotKB Ensembl HPRD

Homo sapiens

PREY

VDAC3

HD-VDAC3, VDAC-3

voltage-dependent anion channel 3

GO Process (1)

GO Function (1)

GO Component (3)

Gene Ontology Biological Process

adenine transport [TAS]

Gene Ontology Molecular Function

voltage-gated anion channel activity [TAS]

Gene Ontology Cellular Component

extracellular vesicular exosome [IDA]

mitochondrion [IDA]

CRISPR Database OMIM VEGA HGNC Alliance of Genome Resources Entrez Gene RefSeq UniprotKB Ensembl HPRD

Homo sapiens

Co-fractionation

Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.

Publication

A census of human soluble protein complexes.

Havugimana PC, Hart GT, Nepusz T, Yang H, Turinsky AL, Li Z, Wang PI, Boutz DR, Fong V, Phanse S, Babu M, Craig SA, Hu P, Wan C, Vlasblom J, Dar VU, Bezginov A, Clark GW, Wu GC, Wodak SJ, Tillier ER, Paccanaro A, Marcotte EM, Emili A

Cellular processes often depend on stable physical associations between proteins. Despite recent progress, knowledge of the composition of human protein complexes remains limited. To close this gap, we applied an integrative global proteomic profiling approach, based on chromatographic separation of cultured human cell extracts into more than one thousand biochemical fractions that were subsequently analyzed by quantitative tandem mass spectrometry, ... [more]

Cell Aug. 31, 2012; 150(5);1068-81 [Pubmed: 22939629]

Quantitative Score

0.889 [Denoised score]

Throughput

High Throughput

Additional Notes

Denoised score >= 0.75

Curated By

BioGRID