BAIT
CALR
CRT, HEL-S-99n, RO, SSA, cC1qR
calreticulin
GO Process (33)
GO Function (15)
GO Component (17)
Gene Ontology Biological Process
- activation of signaling protein activity involved in unfolded protein response [TAS]
- antigen processing and presentation of exogenous peptide antigen via MHC class I [TAS]
- antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [TAS]
- antigen processing and presentation of peptide antigen via MHC class I [TAS]
- cell cycle arrest [IGI]
- cellular calcium ion homeostasis [TAS]
- cellular protein metabolic process [TAS]
- cellular senescence [IGI]
- endoplasmic reticulum unfolded protein response [TAS]
- glucocorticoid receptor signaling pathway [TAS]
- negative regulation of intracellular steroid hormone receptor signaling pathway [IDA]
- negative regulation of neuron differentiation [IDA]
- negative regulation of retinoic acid receptor signaling pathway [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- negative regulation of transcription, DNA-templated [IDA]
- negative regulation of translation [ISS, TAS]
- peptide antigen assembly with MHC class I protein complex [ISS]
- positive regulation of DNA replication [IGI]
- positive regulation of cell cycle [IGI]
- positive regulation of cell proliferation [IGI]
- positive regulation of dendritic cell chemotaxis [IMP]
- positive regulation of phagocytosis [ISS]
- positive regulation of substrate adhesion-dependent cell spreading [IMP]
- post-translational protein modification [TAS]
- protein N-linked glycosylation via asparagine [TAS]
- protein export from nucleus [IDA]
- protein folding [TAS]
- protein localization to nucleus [IDA]
- protein maturation by protein folding [TAS]
- protein stabilization [ISS, TAS]
- regulation of apoptotic process [TAS]
- regulation of transcription, DNA-templated [TAS]
- sequestering of calcium ion [TAS]
Gene Ontology Molecular Function- DNA binding [NAS]
- androgen receptor binding [IDA]
- calcium ion binding [ISS, TAS]
- carbohydrate binding [TAS]
- chaperone binding [TAS]
- complement component C1q binding [TAS]
- glycoprotein binding [IPI]
- integrin binding [IPI]
- mRNA binding [IDA]
- poly(A) RNA binding [IDA]
- protein binding [IPI]
- protein binding involved in protein folding [TAS]
- ubiquitin protein ligase binding [IPI]
- unfolded protein binding [TAS]
- zinc ion binding [TAS]
- DNA binding [NAS]
- androgen receptor binding [IDA]
- calcium ion binding [ISS, TAS]
- carbohydrate binding [TAS]
- chaperone binding [TAS]
- complement component C1q binding [TAS]
- glycoprotein binding [IPI]
- integrin binding [IPI]
- mRNA binding [IDA]
- poly(A) RNA binding [IDA]
- protein binding [IPI]
- protein binding involved in protein folding [TAS]
- ubiquitin protein ligase binding [IPI]
- unfolded protein binding [TAS]
- zinc ion binding [TAS]
Gene Ontology Cellular Component
- MHC class I peptide loading complex [ISS]
- cell surface [TAS]
- cytoplasm [IDA]
- cytosol [IDA]
- endocytic vesicle lumen [TAS]
- endoplasmic reticulum [IDA, TAS]
- endoplasmic reticulum lumen [IDA, TAS]
- extracellular region [TAS]
- extracellular space [IDA]
- extracellular vesicular exosome [IDA]
- focal adhesion [IDA]
- integral component of lumenal side of endoplasmic reticulum membrane [TAS]
- intracellular [TAS]
- membrane [IDA]
- nucleus [IDA]
- perinuclear region of cytoplasm [IDA]
- polysome [ISS]
Homo sapiens
PREY
GANAB
G2AN, GLUII
glucosidase, alpha; neutral AB
GO Process (4)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
A census of human soluble protein complexes.
Cellular processes often depend on stable physical associations between proteins. Despite recent progress, knowledge of the composition of human protein complexes remains limited. To close this gap, we applied an integrative global proteomic profiling approach, based on chromatographic separation of cultured human cell extracts into more than one thousand biochemical fractions that were subsequently analyzed by quantitative tandem mass spectrometry, ... [more]
Cell Aug. 31, 2012; 150(5);1068-81 [Pubmed: 22939629]
Quantitative Score
- 0.854 [Denoised score]
Throughput
- High Throughput
Additional Notes
- Denoised score >= 0.75
Curated By
- BioGRID