BAIT
S100A9
60B8AG, CAGB, CFAG, CGLB, L1AG, LIAG, MAC387, MIF, MRP14, NIF, P14
S100 calcium binding protein A9
GO Process (18)
GO Function (8)
GO Component (7)
Gene Ontology Biological Process
- activation of cysteine-type endopeptidase activity involved in apoptotic process [IDA]
- autophagy [IDA]
- cell-cell signaling [TAS]
- chemokine production [TAS]
- cytokine production [TAS]
- defense response to bacterium [TAS]
- defense response to fungus [TAS]
- inflammatory response [TAS]
- leukocyte migration involved in inflammatory response [IDA]
- neutrophil aggregation [IDA]
- neutrophil chemotaxis [IDA]
- positive regulation of NF-kappaB transcription factor activity [TAS]
- positive regulation of cell growth [TAS]
- positive regulation of inflammatory response [IDA]
- positive regulation of intrinsic apoptotic signaling pathway [IDA]
- regulation of cytoskeleton organization [TAS]
- sequestering of zinc ion [TAS]
- signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
VTN
V75, VN, VNT
vitronectin
GO Process (17)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
- cell adhesion [TAS]
- cell adhesion mediated by integrin [IDA]
- cell-matrix adhesion [IDA]
- endodermal cell differentiation [IDA]
- extracellular matrix organization [TAS]
- immune response [TAS]
- innate immune response [TAS]
- negative regulation of blood coagulation [IC]
- negative regulation of endopeptidase activity [IDA]
- positive regulation of peptidyl-tyrosine phosphorylation [IDA]
- positive regulation of protein binding [IDA]
- positive regulation of receptor-mediated endocytosis [IDA]
- positive regulation of smooth muscle cell migration [IDA]
- positive regulation of vascular endothelial growth factor receptor signaling pathway [TAS]
- positive regulation of wound healing [IC]
- regulation of complement activation [TAS]
- smooth muscle cell-matrix adhesion [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
A census of human soluble protein complexes.
Cellular processes often depend on stable physical associations between proteins. Despite recent progress, knowledge of the composition of human protein complexes remains limited. To close this gap, we applied an integrative global proteomic profiling approach, based on chromatographic separation of cultured human cell extracts into more than one thousand biochemical fractions that were subsequently analyzed by quantitative tandem mass spectrometry, ... [more]
Cell Aug. 31, 2012; 150(5);1068-81 [Pubmed: 22939629]
Quantitative Score
- 0.901 [Denoised score]
Throughput
- High Throughput
Additional Notes
- Denoised score >= 0.75
Curated By
- BioGRID