BAIT
ABCD3
ABC43, PMP70, PXMP1, ZWS2
ATP-binding cassette, sub-family D (ALD), member 3
GO Process (5)
GO Function (4)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
TAP1
ABC17, ABCB2, APT1, D6S114E, PSF-1, PSF1, RING4, TAP1*0102N, TAP1N, DAAP-57C1.5
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
GO Process (8)
GO Function (10)
GO Component (5)
Gene Ontology Biological Process
- antigen processing and presentation of endogenous peptide antigen via MHC class I [IMP]
- antigen processing and presentation of exogenous peptide antigen via MHC class I [TAS]
- antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent [TAS]
- antigen processing and presentation of peptide antigen via MHC class I [TAS]
- cytosol to ER transport [IMP]
- intracellular transport of viral protein in host cell [IMP]
- peptide transport [IMP]
- transmembrane transport [IBA]
Gene Ontology Molecular Function- ADP binding [IDA]
- ATP binding [IDA]
- ATPase activity, coupled to transmembrane movement of substances [IBA]
- MHC class Ib protein binding [IPI]
- TAP1 binding [ISS]
- TAP2 binding [IPI]
- peptide antigen binding [NAS]
- peptide transporter activity [IGI, IMP]
- protein binding [IPI]
- protein homodimerization activity [ISS]
- ADP binding [IDA]
- ATP binding [IDA]
- ATPase activity, coupled to transmembrane movement of substances [IBA]
- MHC class Ib protein binding [IPI]
- TAP1 binding [ISS]
- TAP2 binding [IPI]
- peptide antigen binding [NAS]
- peptide transporter activity [IGI, IMP]
- protein binding [IPI]
- protein homodimerization activity [ISS]
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
A census of human soluble protein complexes.
Cellular processes often depend on stable physical associations between proteins. Despite recent progress, knowledge of the composition of human protein complexes remains limited. To close this gap, we applied an integrative global proteomic profiling approach, based on chromatographic separation of cultured human cell extracts into more than one thousand biochemical fractions that were subsequently analyzed by quantitative tandem mass spectrometry, ... [more]
Cell Aug. 31, 2012; 150(5);1068-81 [Pubmed: 22939629]
Quantitative Score
- 0.822 [Denoised score]
Throughput
- High Throughput
Additional Notes
- Denoised score >= 0.75
Curated By
- BioGRID