BAIT
PRDX5
ACR1, AOEB166, B166, HEL-S-55, PLP, PMP20, PRDX6, PRXV, prx-V, SBBI10
peroxiredoxin 5
GO Process (12)
GO Function (8)
GO Component (12)
Gene Ontology Biological Process
- NADPH oxidation [IDA]
- cellular response to reactive oxygen species [IMP]
- hydrogen peroxide catabolic process [IDA]
- inflammatory response [TAS]
- negative regulation of apoptotic process [IMP]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [IMP]
- negative regulation of oxidoreductase activity [IDA]
- negative regulation of transcription from RNA polymerase III promoter [IDA]
- positive regulation of collagen biosynthetic process [IDA]
- reactive nitrogen species metabolic process [IDA]
- regulation of apoptosis involved in tissue homeostasis [IDA]
- response to oxidative stress [IDA]
Gene Ontology Molecular Function- RNA polymerase III regulatory region DNA binding [IDA]
- antioxidant activity [IDA]
- cysteine-type endopeptidase inhibitor activity involved in apoptotic process [IMP]
- peroxidase activity [IDA]
- peroxiredoxin activity [IDA]
- peroxynitrite reductase activity [IDA]
- protein dimerization activity [IDA]
- receptor binding [IPI]
- RNA polymerase III regulatory region DNA binding [IDA]
- antioxidant activity [IDA]
- cysteine-type endopeptidase inhibitor activity involved in apoptotic process [IMP]
- peroxidase activity [IDA]
- peroxiredoxin activity [IDA]
- peroxynitrite reductase activity [IDA]
- protein dimerization activity [IDA]
- receptor binding [IPI]
Gene Ontology Cellular Component
- cytoplasm [IDA]
- cytoplasmic vesicle [IDA]
- cytosol [IDA, TAS]
- extracellular space [IDA]
- extracellular vesicular exosome [IDA]
- intracellular membrane-bounded organelle [IDA]
- mitochondrial matrix [TAS]
- mitochondrion [IDA]
- nucleus [IDA]
- perinuclear region of cytoplasm [IDA]
- peroxisomal matrix [IDA]
- peroxisome [IDA]
Homo sapiens
PREY
PTPN23
HD-PTP, HDPTP, PTP-TD14
protein tyrosine phosphatase, non-receptor type 23
GO Process (7)
GO Function (3)
GO Component (7)
Gene Ontology Biological Process
- cilium morphogenesis [IMP]
- negative regulation of epithelial cell migration [IMP]
- peptidyl-tyrosine dephosphorylation [IMP]
- positive regulation of adherens junction organization [IMP]
- positive regulation of early endosome to late endosome transport [IMP]
- positive regulation of homophilic cell adhesion [IMP]
- ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
A census of human soluble protein complexes.
Cellular processes often depend on stable physical associations between proteins. Despite recent progress, knowledge of the composition of human protein complexes remains limited. To close this gap, we applied an integrative global proteomic profiling approach, based on chromatographic separation of cultured human cell extracts into more than one thousand biochemical fractions that were subsequently analyzed by quantitative tandem mass spectrometry, ... [more]
Cell Aug. 31, 2012; 150(5);1068-81 [Pubmed: 22939629]
Quantitative Score
- 0.804 [Denoised score]
Throughput
- High Throughput
Additional Notes
- Denoised score >= 0.75
Curated By
- BioGRID