BAIT

NUP43

bA350J20.1, p42

nucleoporin 43kDa

GO Process (10)

GO Function (1)

GO Component (4)

Gene Ontology Biological Process

carbohydrate metabolic process [TAS]

cytokine-mediated signaling pathway [TAS]

glucose transport [TAS]

hexose transport [TAS]

mitotic cell cycle [TAS]

mitotic nuclear envelope disassembly [TAS]

regulation of glucose transport [TAS]

small molecule metabolic process [TAS]

transmembrane transport [TAS]

viral process [TAS]

Gene Ontology Molecular Function

protein binding [IPI]

Gene Ontology Cellular Component

kinetochore [IDA]

nuclear envelope [TAS]

nuclear pore outer ring [IDA, NAS]

CRISPR Database OMIM HGNC Alliance of Genome Resources Entrez Gene RefSeq UniprotKB Ensembl

Homo sapiens

PREY

RAB3GAP2

RAB3-GAP150, RAB3GAP150, SPG69, WARBM2, p150, RP11-568G11.1

RAB3 GTPase activating protein subunit 2 (non-catalytic)

GO Process (7)

GO Function (5)

GO Component (3)

Gene Ontology Biological Process

establishment of protein localization to endoplasmic reticulum membrane [IMP]

intracellular protein transport [TAS]

positive regulation of GTPase activity [TAS]

positive regulation of Rab GTPase activity [IMP]

positive regulation of catalytic activity [TAS]

positive regulation of endoplasmic reticulum tubular network organization [IMP]

regulation of GTPase activity [ISS]

Gene Ontology Molecular Function

Rab GTPase binding [IPI]
Rab guanyl-nucleotide exchange factor activity [IMP]
enzyme activator activity [TAS]
enzyme regulator activity [ISS]
protein heterodimerization activity [ISS]

Gene Ontology Cellular Component

cytoplasm [IDA]

plasma membrane [IDA]

protein complex [IDA]

CRISPR Database OMIM HGNC Alliance of Genome Resources Entrez Gene RefSeq UniprotKB Ensembl

Homo sapiens

Co-fractionation

Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.

Publication

A census of human soluble protein complexes.

Havugimana PC, Hart GT, Nepusz T, Yang H, Turinsky AL, Li Z, Wang PI, Boutz DR, Fong V, Phanse S, Babu M, Craig SA, Hu P, Wan C, Vlasblom J, Dar VU, Bezginov A, Clark GW, Wu GC, Wodak SJ, Tillier ER, Paccanaro A, Marcotte EM, Emili A

Cellular processes often depend on stable physical associations between proteins. Despite recent progress, knowledge of the composition of human protein complexes remains limited. To close this gap, we applied an integrative global proteomic profiling approach, based on chromatographic separation of cultured human cell extracts into more than one thousand biochemical fractions that were subsequently analyzed by quantitative tandem mass spectrometry, ... [more]

Cell Aug. 31, 2012; 150(5);1068-81 [Pubmed: 22939629]

Quantitative Score

0.804 [Denoised score]

Throughput

High Throughput

Additional Notes

Denoised score >= 0.75

Curated By

BioGRID