BAIT

MED18

p28b
mediator complex subunit 18
GO Process (0)
GO Function (1)
GO Component (1)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

PIP4K2B

PI5P4KB, PIP5K2B, PIP5KIIB, PIP5KIIbeta
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
Autophagy Project
Homo sapiens

Co-fractionation

Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.

Publication

A census of human soluble protein complexes.

Havugimana PC, Hart GT, Nepusz T, Yang H, Turinsky AL, Li Z, Wang PI, Boutz DR, Fong V, Phanse S, Babu M, Craig SA, Hu P, Wan C, Vlasblom J, Dar VU, Bezginov A, Clark GW, Wu GC, Wodak SJ, Tillier ER, Paccanaro A, Marcotte EM, Emili A

Cellular processes often depend on stable physical associations between proteins. Despite recent progress, knowledge of the composition of human protein complexes remains limited. To close this gap, we applied an integrative global proteomic profiling approach, based on chromatographic separation of cultured human cell extracts into more than one thousand biochemical fractions that were subsequently analyzed by quantitative tandem mass spectrometry, ... [more]

Cell Aug. 31, 2012; 150(5);1068-81 [Pubmed: 22939629]

Quantitative Score

  • 0.786 [Denoised score]

Throughput

  • High Throughput

Additional Notes

  • Denoised score >= 0.75

Curated By

  • BioGRID