BAIT
HTRA2
OMI, PARK13, PRSS25
HtrA serine peptidase 2
GO Process (19)
GO Function (5)
GO Component (11)
Gene Ontology Biological Process
- cellular protein catabolic process [IDA]
- cellular response to growth factor stimulus [IMP]
- cellular response to heat [IDA]
- cellular response to interferon-beta [IDA]
- cellular response to oxidative stress [NAS]
- cellular response to retinoic acid [IDA]
- execution phase of apoptosis [TAS]
- intrinsic apoptotic signaling pathway in response to DNA damage [IMP]
- negative regulation of cell cycle [TAS]
- negative regulation of neuron death [TAS]
- negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [NAS]
- positive regulation of apoptotic process [IMP, TAS]
- positive regulation of cell death [IDA]
- positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [IDA]
- positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway [IMP]
- positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [IMP]
- protein autoprocessing [TAS]
- proteolysis [IMP, TAS]
- regulation of mitochondrion degradation [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
NDUFV1
CI-51K, CI51KD, UQOR1
NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
GO Process (4)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
A census of human soluble protein complexes.
Cellular processes often depend on stable physical associations between proteins. Despite recent progress, knowledge of the composition of human protein complexes remains limited. To close this gap, we applied an integrative global proteomic profiling approach, based on chromatographic separation of cultured human cell extracts into more than one thousand biochemical fractions that were subsequently analyzed by quantitative tandem mass spectrometry, ... [more]
Cell Aug. 31, 2012; 150(5);1068-81 [Pubmed: 22939629]
Quantitative Score
- 0.759 [Denoised score]
Throughput
- High Throughput
Additional Notes
- Denoised score >= 0.75
Curated By
- BioGRID