BAIT
PPIF
CYP3, CyP-M, Cyp-D, CypD, RP11-342M3.4
peptidylprolyl isomerase F
GO Process (15)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
- cellular response to arsenic-containing substance [ISS]
- cellular response to calcium ion [ISS]
- cellular response to hydrogen peroxide [IMP]
- negative regulation of ATPase activity [ISS]
- negative regulation of apoptotic process [IDA]
- negative regulation of intrinsic apoptotic signaling pathway [IMP]
- negative regulation of oxidative phosphorylation [ISS]
- negative regulation of oxidative phosphorylation uncoupler activity [ISS]
- negative regulation of release of cytochrome c from mitochondria [IDA]
- positive regulation of release of cytochrome c from mitochondria [ISS]
- protein peptidyl-prolyl isomerization [IBA]
- regulation of mitochondrial membrane permeability [ISS]
- regulation of mitochondrial membrane permeability involved in programmed necrotic cell death [IMP]
- regulation of proton-transporting ATPase activity, rotational mechanism [ISS]
- response to ischemia [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
PTPN11
BPTP3, CFC, NS1, PTP-1D, PTP2C, SH-PTP2, SH-PTP3, SHP2
protein tyrosine phosphatase, non-receptor type 11
GO Process (27)
GO Function (6)
GO Component (3)
Gene Ontology Biological Process
- ERBB signaling pathway [IDA]
- Fc-epsilon receptor signaling pathway [TAS]
- T cell costimulation [TAS]
- atrioventricular canal development [IMP]
- axon guidance [TAS]
- blood coagulation [TAS]
- brain development [IMP]
- cytokine-mediated signaling pathway [TAS]
- ephrin receptor signaling pathway [IDA]
- epidermal growth factor receptor signaling pathway [TAS]
- face morphogenesis [IMP]
- fibroblast growth factor receptor signaling pathway [TAS]
- genitalia development [IMP]
- heart development [IMP]
- innate immune response [TAS]
- inner ear development [IMP]
- insulin receptor signaling pathway [TAS]
- interferon-gamma-mediated signaling pathway [TAS]
- leukocyte migration [TAS]
- neurotrophin TRK receptor signaling pathway [TAS]
- peptidyl-tyrosine dephosphorylation [IDA, IMP]
- phosphatidylinositol-mediated signaling [TAS]
- positive regulation of glucose import in response to insulin stimulus [IDA]
- regulation of cell adhesion mediated by integrin [IMP]
- regulation of interferon-gamma-mediated signaling pathway [TAS]
- regulation of type I interferon-mediated signaling pathway [TAS]
- type I interferon signaling pathway [TAS]
Gene Ontology Molecular Function
Homo sapiens
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
A census of human soluble protein complexes.
Cellular processes often depend on stable physical associations between proteins. Despite recent progress, knowledge of the composition of human protein complexes remains limited. To close this gap, we applied an integrative global proteomic profiling approach, based on chromatographic separation of cultured human cell extracts into more than one thousand biochemical fractions that were subsequently analyzed by quantitative tandem mass spectrometry, ... [more]
Cell Aug. 31, 2012; 150(5);1068-81 [Pubmed: 22939629]
Quantitative Score
- 0.758 [Denoised score]
Throughput
- High Throughput
Additional Notes
- Denoised score >= 0.75
Curated By
- BioGRID