BAIT
PRRC2A
BAT2, D6S51, D6S51E, G2, DADB-70P7.5
proline-rich coiled-coil 2A
GO Process (0)
GO Function (2)
GO Component (4)
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
CPSF1
CPSF160, HSU37012, P/cl.18
cleavage and polyadenylation specific factor 1, 160kDa
GO Process (9)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region.
High-throughput (HTP) protein-interaction assays, such as the yeast two-hybrid (Y2H) system, are enormously useful in predicting the functions of novel gene-products. HTP-Y2H screens typically do not include all of the reconfirmation and specificity tests used in small-scale studies, but the effects of omitting these steps have not been assessed. We performed HTP-Y2H screens that included all standard controls, using the ... [more]
Genomics Jan. 01, 2004; 83(1);153-67 [Pubmed: 14667819]
Throughput
- Low Throughput
Curated By
- BioGRID