WFIKKN2
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
MSTN
Gene Ontology Biological Process
- SMAD protein signal transduction [IBA]
- cell development [IBA]
- cellular response to dexamethasone stimulus [IDA]
- negative regulation of muscle hypertrophy [ISO]
- negative regulation of skeletal muscle tissue growth [ISO]
- positive regulation of pathway-restricted SMAD protein phosphorylation [IBA]
- positive regulation of transcription, DNA-templated [ISO]
- regulation of MAPK cascade [IBA]
- regulation of apoptotic process [IBA]
- transforming growth factor beta receptor signaling pathway [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Regulation of myostatin in vivo by growth and differentiation factor-associated serum protein-1: a novel protein with protease inhibitor and follistatin domains.
Myostatin, a member of the TGFbeta superfamily, is a potent and specific negative regulator of skeletal muscle mass. In serum, myostatin circulates as part of a latent complex containing myostatin propeptide and/or follistatin-related gene (FLRG). Here, we report the identification of an additional protein associated with endogenous myostatin in normal mouse and human serum, discovered by affinity purification and mass ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID