BAIT

GEMIN6

gem (nuclear organelle) associated protein 6
GO Process (5)
GO Function (1)
GO Component (6)
Homo sapiens
PREY

RNU2-1

RNU2, U2
RNA, U2 small nuclear 1
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens

Protein-RNA

An interaction is detected between and protein and an RNA in vitro.

Publication

Implication of the SMN complex in the biogenesis and steady state level of the Signal Recognition Particle.

Piazzon N, Schlotter F, Lefebvre S, Dodre M, Mereau A, Soret J, Besse A, Barkats M, Bordonne R, Branlant C, Massenet S

Spinal muscular atrophy is a severe motor neuron disease caused by reduced levels of the ubiquitous Survival of MotoNeurons (SMN) protein. SMN is part of a complex that is essential for spliceosomal UsnRNP biogenesis. Signal recognition particle (SRP) is a ribonucleoprotein particle crucial for co-translational targeting of secretory and membrane proteins to the endoplasmic reticulum. SRP biogenesis is a nucleo-cytoplasmic ... [more]

Nucleic Acids Res. Dec. 05, 2012; 0(0); [Pubmed: 23221635]

Throughput

  • Low Throughput

Curated By

  • BioGRID