PRKCB
Gene Ontology Biological Process
- B cell activation [IMP]
- B cell receptor signaling pathway [IMP]
- calcium ion transport [IDA]
- cellular calcium ion homeostasis [IDA]
- cellular response to carbohydrate stimulus [IDA]
- histone H3-T6 phosphorylation [ISO]
- negative regulation of glucose transport [IMP]
- negative regulation of insulin receptor signaling pathway [ISO]
- positive regulation of B cell receptor signaling pathway [IMP]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [IMP]
- positive regulation of NF-kappaB transcription factor activity [IMP]
- positive regulation of angiogenesis [IMP]
- positive regulation of vascular endothelial growth factor receptor signaling pathway [IMP]
- protein phosphorylation [IDA]
- regulation of dopamine secretion [ISO]
- regulation of growth [ISO]
- regulation of transcription from RNA polymerase II promoter [ISO]
- response to drug [ISO]
- response to hypoxia [IDA]
Gene Ontology Molecular Function- androgen receptor binding [ISO]
- calcium channel regulator activity [IDA]
- chromatin binding [ISO]
- histone binding [ISO]
- histone kinase activity (H3-T6 specific) [ISO]
- ligand-dependent nuclear receptor transcription coactivator activity [ISO]
- protein binding [IPI]
- protein kinase C activity [IDA, ISO]
- protein kinase C binding [ISO]
- protein serine/threonine kinase activity [IDA]
- androgen receptor binding [ISO]
- calcium channel regulator activity [IDA]
- chromatin binding [ISO]
- histone binding [ISO]
- histone kinase activity (H3-T6 specific) [ISO]
- ligand-dependent nuclear receptor transcription coactivator activity [ISO]
- protein binding [IPI]
- protein kinase C activity [IDA, ISO]
- protein kinase C binding [ISO]
- protein serine/threonine kinase activity [IDA]
Gene Ontology Cellular Component
GAP43
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Biochemical Activity (Phosphorylation)
An interaction is inferred from the biochemical effect of one protein upon another, for example, GTP-GDP exchange activity or phosphorylation of a substrate by a kinase. The bait protein executes the activity on the substrate hit protein. A Modification value is recorded for interactions of this type with the possible values Phosphorylation, Ubiquitination, Sumoylation, Dephosphorylation, Methylation, Prenylation, Acetylation, Deubiquitination, Proteolytic Processing, Glucosylation, Nedd(Rub1)ylation, Deacetylation, No Modification, Demethylation.
Publication
Phosphorylation of GAP-43 (growth-associated protein of 43 kDa) by conventional, novel and atypical isotypes of the protein kinase C gene family: differences between oligopeptide and polypeptide phosphorylation.
GAP-43 (growth-associated protein of 43 kDa; also known as neuromodulin, P-57, B-50 and F-1) is a neuronal calmodulin binding protein and a major protein kinase C (PKC) substrate in mammalian brain. Here we describe the phosphorylation by and the site specificity of different PKC isotypes. The conventional PKC beta 1 and the novel PKCs delta and epsilon effectively phosphorylated recombinant ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID