BAIT

TIA1

TIA-1, WDM
TIA1 cytotoxic granule-associated RNA binding protein
Alzheimer's Disease Project
GO Process (1)
GO Function (3)
GO Component (4)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

WDR6

WD repeat domain 6
GO Process (3)
GO Function (2)
GO Component (3)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Co-localization

Interaction inferred from two proteins that co-localize in the cell by indirect immunofluorescence only when in addition, if one gene is deleted, the other protein becomes mis-localized. Also includes co-dependent association of proteins with promoter DNA in chromatin immunoprecipitation experiments.

Publication

A novel c-Jun N-terminal kinase (JNK)-binding protein WDR62 is recruited to stress granules and mediates a nonclassical JNK activation.

Wasserman T, Katsenelson K, Daniliuc S, Hasin T, Choder M, Aronheim A

The c-Jun N-terminal kinase (JNK) is part of a mitogen-activated protein kinase (MAPK) signaling cascade. Scaffold proteins simultaneously associate with various components of the MAPK signaling pathway and play a role in signal transmission and regulation. Here we describe the identification of a novel scaffold JNK-binding protein, WDR62, with no sequence homology to any of the known scaffold proteins. WDR62 ... [more]

Mol. Biol. Cell Jan. 01, 2010; 21(1);117-30 [Pubmed: 19910486]

Throughput

  • Low Throughput

Additional Notes

  • figure S4.

Curated By

  • BioGRID