BAIT

TUBG1

CDCBM4, GCP-1, TUBG, TUBGCP1
tubulin, gamma 1
Homo sapiens
PREY

CCP110

CP110, Cep110
centriolar coiled coil protein 110kDa
GO Process (5)
GO Function (1)
GO Component (4)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Co-fractionation

Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.

Publication

CP110, a cell cycle-dependent CDK substrate, regulates centrosome duplication in human cells.

Chen Z, Indjeian VB, McManus M, Wang L, Dynlacht BD

Centrosome duplication and separation are linked inextricably to certain cell cycle events, in particular activation of cyclin-dependent kinases (CDKs). However, relatively few CDK targets driving these events have been uncovered. Here, we have performed a screen for CDK substrates and have isolated a target, CP110, which is phosphorylated by CDKs in vitro and in vivo. Human CP110 localizes to centrosomes. ... [more]

Dev. Cell Sep. 01, 2002; 3(3);339-50 [Pubmed: 12361598]

Throughput

  • Low Throughput

Additional Notes

  • figure 5.

Curated By

  • BioGRID