TOB2
Gene Ontology Biological Process
Gene Ontology Molecular Function
L1CAM
Gene Ontology Biological Process
- axon guidance [ISO]
- cell surface receptor signaling pathway [ISO]
- cell-cell adhesion mediated by integrin [ISO]
- cellular response to ethanol [IEP]
- cellular response to transforming growth factor beta stimulus [IEP]
- heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [ISO]
- homophilic cell adhesion via plasma membrane adhesion molecules [ISO]
- homotypic cell-cell adhesion [ISO]
- leukocyte cell-cell adhesion [ISO]
- neuron projection development [ISO]
- positive regulation of calcium-mediated signaling [ISO]
- positive regulation of cell-cell adhesion [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Comparative peptide binding studies of the PABC domains from the ubiquitin-protein isopeptide ligase HYD and poly(A)-binding protein. Implications for HYD function.
The PABC domain is a peptide-binding domain that is specifically found in poly(A)-binding protein (PABP) and a HECT ubiquitin-protein isopeptide ligase (E3) known as HYD (hyperplastic discs), EDD (E3 isolated by differential display), or Rat100. The PABC domain of PABP recruits various regulatory proteins and translation factors to poly(A) mRNAs through binding of a conserved 12-amino acid peptide motif, PAM2 ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| L1CAM TOB2 | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - |
Curated By
- BioGRID