B4GALT1
Gene Ontology Biological Process
- acute inflammatory response [IMP]
- angiogenesis involved in wound healing [IMP]
- binding of sperm to zona pellucida [IMP, IPI]
- branching morphogenesis of an epithelial tube [IMP]
- cell adhesion [IGI]
- development of secondary sexual characteristics [IMP]
- epithelial cell development [IMP]
- extracellular matrix organization [IMP]
- galactose metabolic process [IDA]
- glycoprotein biosynthetic process [IMP]
- lactose biosynthetic process [IMP]
- leukocyte migration [IMP]
- mammary gland development [IMP]
- negative regulation of cell proliferation [IGI, IMP]
- oligosaccharide biosynthetic process [IDA, ISO]
- penetration of zona pellucida [IMP]
- positive regulation of apoptotic process [IMP]
- positive regulation of apoptotic process involved in mammary gland involution [IMP]
- positive regulation of epithelial cell proliferation involved in wound healing [IMP]
- protein N-linked glycosylation [ISO]
- protein glycosylation [IMP]
- regulation of acrosome reaction [IMP]
- regulation of cell proliferation [IMP]
- regulation of cellular component movement [IDA]
- wound healing [IMP]
Gene Ontology Molecular Function- N-acetyllactosamine synthase activity [ISO]
- UDP-galactosyltransferase activity [ISO]
- alpha-tubulin binding [ISO]
- beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [IDA, IMP, ISO]
- beta-tubulin binding [ISO]
- cytoskeletal protein binding [IDA]
- galactosyltransferase activity [IDA]
- lactose synthase activity [ISO]
- manganese ion binding [ISO]
- protein binding [IPI]
- protein homodimerization activity [ISO]
- protein kinase binding [ISO]
- N-acetyllactosamine synthase activity [ISO]
- UDP-galactosyltransferase activity [ISO]
- alpha-tubulin binding [ISO]
- beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity [IDA, IMP, ISO]
- beta-tubulin binding [ISO]
- cytoskeletal protein binding [IDA]
- galactosyltransferase activity [IDA]
- lactose synthase activity [ISO]
- manganese ion binding [ISO]
- protein binding [IPI]
- protein homodimerization activity [ISO]
- protein kinase binding [ISO]
Gene Ontology Cellular Component
- Golgi apparatus [IDA, ISO]
- Golgi trans cisterna [ISO]
- basolateral plasma membrane [ISO]
- brush border membrane [ISO]
- cell surface [IDA, IMP]
- desmosome [ISO]
- external side of plasma membrane [ISO]
- extracellular space [ISO]
- extracellular vesicular exosome [ISO]
- glycocalyx [ISO]
- membrane [ISO]
- plasma membrane [IDA]
UBE2Q1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Characterization of a novel ubiquitin-conjugating enzyme that regulates beta1,4-galactosyltransferase-1 in embryonic stem cells.
In this study we identified a novel galactosyltransferase 1-associating protein (GTAP) by cDNA cloning from a murine embryonic cDNA library using the two-hybrid yeast system. GTAP is expressed in early embryonic tissues, as well as in adult tissues with active cell turnover, and belongs to the class III ubiquitin-conjugating (E2) enzyme family. Its COOH-terminal domain contains a consensus sequence for ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| UBE2Q1 B4GALT1 | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - | |
| B4GALT1 UBE2Q1 | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | Low | - | BioGRID | - |
Curated By
- BioGRID