DAG1
Gene Ontology Biological Process
- NLS-bearing protein import into nucleus [ISO]
- Schwann cell development [IMP]
- basement membrane organization [IMP]
- branching involved in salivary gland morphogenesis [IMP]
- calcium-dependent cell-matrix adhesion [ISO]
- commissural neuron axon guidance [IMP]
- cytoskeletal anchoring at plasma membrane [ISO]
- epithelial tube branching involved in lung morphogenesis [IMP]
- membrane protein ectodomain proteolysis [ISO]
- microtubule anchoring [ISO]
- modulation by virus of host morphology or physiology [ISO]
- morphogenesis of an epithelial sheet [IMP]
- myelination in peripheral nervous system [IMP]
- negative regulation of MAPK cascade [ISO]
- negative regulation of cell migration [ISO]
- negative regulation of protein kinase B signaling [ISO]
- nerve maturation [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- basement membrane [IDA, ISO]
- basolateral plasma membrane [ISO]
- cell outer membrane [IDA]
- cell-cell adherens junction [ISO]
- cell-cell junction [IDA]
- contractile ring [ISO]
- costamere [ISO]
- cytoplasm [ISO]
- dystroglycan complex [IDA]
- dystrophin-associated glycoprotein complex [ISO]
- extracellular space [ISO]
- extracellular vesicular exosome [ISO]
- filopodium [ISO]
- focal adhesion [ISO]
- integral component of membrane [ISO]
- lamellipodium [ISO]
- membrane [IDA]
- membrane raft [IDA]
- node of Ranvier [IMP]
- nucleoplasm [ISO]
- plasma membrane [IDA, ISO]
- sarcolemma [IDA, ISO]
SGCD
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Association of dystrophin-related protein with dystrophin-associated proteins in mdx mouse muscle.
Dystrophin is associated with a complex of muscle membrane (sarcolemmal) glycoproteins that provide a linkage to the extracellular matrix protein, laminin. The absence of dystrophin leads to a dramatic reduction of the dystrophin-associated proteins (156DAG, 59DAP, 50DAG, 43DAG and 35DAG) in the sarcolemma of patients with Duchenne muscular dystrophy and mdx mice. Here we demonstrate that dystrophin-related protein (DRP, utrophin), ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| DAG1 SGCD | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - |
Curated By
- BioGRID